4日前 -Suggest possible role for tau protein as a prognostic factor to predict progression from optic neuritis to multiple sclerosis. human HTRA1 degrades ...
2日前 -Pierre-Emmanuel Rautou; Johanne Poisson. News & Views 14 Jun 2024. Redefining common and rare HTRA1 variants as risk factors for polyvascular disease. Stéphanie ...
2日前 -to study the effect of TGF-β on HTRA1 (high-temperature requirement A1)-affected Wnt target genes.[6]. Biochem/physiol Actions. TGF-β1 is a multifunctional ...
4日前 -One of the targets of HtrA1 activity during fetal development is the TSC2-TSC1 pathway. Lymphangioleiomyomatosis (LAM), occurring sporadically (S-LAM) or in ...
1日前 -Purpose: A single-nucleotide polymorphism in HTRA1 has been linked to age-related macular degeneration (AMD). Here we investigated the potential links between ...
4日前 -Rare mutations in the high requirement temperature protein A1 (HTRA1) cause cerebral vasculopathy. Here, authors establish mechanistically distinct protein ...
1日前 -Here, we show that the cell-to-cell transfer of the widely conserved serine protease HTRA1 impedes tau pathology by targeting multiple steps within the ...
4日前 -These previous studies have identified multiple CAA-associated proteins such as HTRA1, SMOC1, SMOC2, and SRPX1 [20, 23, 26, 45, 72, 75]. However it is still not ...
4日前 -Serine protease HTRA1 is known to regulate the availability of insulin-like growth factors (IGFs) by cleaving their binding proteins (IGFBPs) [(31)]. IGFs and ...
3日前 -of HTRA1 in human retinal pigment epithelium. Proceedings of the National Academy of Sciences of the United States of America. 2021;118(30). 10. Stone EM ...