2024/5/14 -HTRA1 interacts with SLC7A11 to modulate colorectal cancer chemosensitivity by inhibiting ferroptosis ... Gain- and loss-of-function analyses demonstrated a ...
1日前 -The initial hits were optimized by using affinity maturation strategies to yield highly selective and potent picomolar inhibitors of HTRA1. Crystal structures, ...
HTRA1 contains four functional domains, including PDZ domain, serine protease domain, insulin-1ike growth factor binding protein domain, and Kazal structural ...
2日前 -HTRA1 forms a homotrimer through its protease domains that positions the three active sites in close proximity such that antibodies are unable to simultaneously ...
1日前 -“HTRA1 has proven to be a risk gene for various disorders, including stroke and diseases of the cerebral small vessels,” explains the stroke and dementia ...
3日前 -“HTRA1 has proven to be a risk gene for various disorders, including stroke and diseases of the cerebral small vessels,” explains the stroke and dementia ...
2日前 -"HTRA1 has proven to be a risk gene for various disorders, including stroke and diseases of the cerebral small vessels," explains the researcher. People who ...
2024/5/15 -HtrA serine protease 1 (HTRA1) was screened out as a colorectal cancer (CRC) progression- and chemoresistance-related gene. Gain- and loss-of-function ...
3日前 -Interestingly, HTRA1 is necessary for muscle development and for the build-up of muscle's anticancer protein arsenal, which contributes to our muscle being our ...
3日前 -Interestingly, HTRA1 is necessary for muscle development and for the build-up of muscle's anticancer protein arsenal, which contributes to our muscle being our ...