Pre-show drink mixing with Richard Garriott and Yuri's Night Chief Mixologist Lauren Paylor

Dr. Brian May, lead guitarist of Queen and astrophysicist, welcomes you to Yuri's Night 2021

George and Loretta Whitesides, co-creators of Yuri's Night, welcome you to Yuri's Night

George and Loretta talk with business magnate and explorer Sir Richard Branson, founder of Virgin Galactic

Joe Rohde explains why he joined Virgin Galactic to design the experience of private space travel

Preview of Woman in Motion, the story of Nichelle Nichols' partnership with NASA

Rhyming NASA KSC Assoicate Director Kelvin Manning speaks about NASA's renewed emphasis on diversity, equity, and inclusion

Robert (Bob) Crippen tells us what it was like to be the pilot of STS-1, the first space shuttle flight in 1981. Hear more on planetary.org/radio

Second-generation space explorer Richard Garriott discusses malfunctions during spaceflight with ESA Italian Astronaut Luca Parmitano

Audio from Yuri Gagarin's launch to space on April 12, 1961

Astronaut Ron Garan, author of "The Orbial Perspective" wishes you a Happy Yuri's Night

George talks to stars of The Expanse, Nadine Nicole and Wes Chatham

Loretta talks to NASA Astronaut Leland Melvin about his NASA experience and inspiring others to follow his journey

Frank White, author of The Overview Effect introduces the trailer for The High Frontier, premiering on SpaceChannel.com on April 17

Loretta talks with Diana Trujillo and Karen Lee from the Jet Propulsion Lab (JPL) Mars Ingenuity Helicopter team about powered flight on another planet

Time-lapse digital art by Cathrin Machin

Niko Blanks and space Youtube celebrities Tim Dodd (@EverydayAstronaut ) & @simonegiertz discuss the Cosmic Odyssey Scholarship that Niko has created to send pediatric cancer patients to Space Camp

Aerospace Engineer & cuber Bailey Burns (@ninjaneergirl) introduces us to Paragon Space Development Corp and CEO Grant Anderson and the life support technologies that Paragon builds for human spaceflight

Dr. Ryan Kobrick introduces the CEO of the Planetary Society Bill Nye who is joined by Astronaut Teacher Mike Mongo to talk about the future of space exploration

Time-lapse digital art by Sergio Vazquez

Yuri's Night Director Tim Baily interviews Inspiration4 Astronaut Chris Sembroski

Loretta introduces the @okgo "Upside Down & Inside Out" video that inspired our team to honor the band with the 2020 Spirit of Yuri's Night award

Tim talks to Damian Kulash, lead signer and guitarist of OK Go, about filming in zero-g and their new OK Go Sandbox project "All Together Now"

Sergei Krikalev explains how all of us share one big spacecraft together, the Earth

George and Loretta close the show, thanking the guests, cast, and crew of this amazing event!