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Hydrophilic interaction is prominent once the mobile phase includes at least 60% organic solvent.
The mechanism of HILIC involves partitioning between a water-enriched layer that is partially immobilized
Instrumentally speaking, a chromatographic system for HILIC chromatography is virtually equivalent
The stationary phase in HILIC columns is hydrophilic and frequently also charged, at least in some pH ranges.
Compounds separated on the column interact with the stationary phase
It is used to determine the concentrations of dimethindene maleate in topical gel