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Our brains are made up of billions of neurons.
Those neurons communicate by sending chemical neurotransmitters to each other at junctions called synapses.
Some of these synapses send excitatory neurotransmitters...
how does each cell know where it should connect with other cells?
When they released an excitatory neurotransmitter, glutamate, the synapses became mostly excitatory.
The findings suggest that GABA sets the balance between inhibitory & excitatory synapses in early development, laying the foundation for circuit formation.
The team, led by Hyungbae Kwon, Ph.D., published their findings in Science.
Their work could impact how we understand and treat developmental disorders.