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Tenofovir causes mitochondria toxicity in renal proximal tubular cells
Low body weight is a risk factor for TDF-nephrotoxicity
Results (n=792)
Subgroup analysis stratified by body weight
2. Single-center study to investigate incidence of CKD and renal function
ART initiation was associated with a faster rate of eGFR decline
Initiation of TDF-containing ART was significantly associated with a faster rate of eGFR decline
Conclusions
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