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The ALK inhibitor crizotinib was shown to be superior to platinum-based chemotherapy as first-line therapy for NSCLC; subsequent trials ...
Facebook-The New England Journal of Medicine
2020/11/19Tony Mok, MD, and David Spigel, MD, provide insight on crizotinib resistance in ALK-positive non–small cell lung cancer.
YouTube-OncLiveTV
2017/01/31Alice T. Shaw, MD, PhD; Gregory J. Riely, MD; and Mark A. Socinski, MD, explain the use of ceritinib with crizotinib-treated patients and ...
YouTube-OncLiveTV
2016/02/04... crizotinib in the first-line treatment of patients with advanced ALK-positive non-small cell lung cancer (NSCLC). Lorlatinib resulted in a ...
YouTube-VJOncology
2020/10/06Lead author, Alice T. Shaw, MD, PhD, an attending physician in the Center for Thoracic Cancers at Massachusetts General Hospital, ...
YouTube-OncLiveTV
2013/07/19... crizotinib. Multivariate analysis reveals that high tumor burden (hTB) is a prognostic factor for worse PFS regardless of treatment, while a ...
YouTube-VJOncology
2023/11/21The 17th European Congress: Perspectives in Lung Cancer, held from 4-5 March 2016 in Prague, provided attendees with valuable information ...
YouTube-HMP Education
2016/03/23Earn CME for related activities: https://hmpeducation.com/ In this presentation from the 22nd Annual Perspectives in Thoracic Oncology, ...
YouTube-HMP Education
2018/02/12動画の見どころ1/10枚目 Oncogenic Drivers in NSCLC
動画の見どころ2/10枚目 Establishing First-Line Therapy for ALK+ NSCLC
動画の見どころ3/10枚目 ASCEND-4: Phase III Study of 1L Ceritinib vs Platinum/Pemetrexed Chemotherapy
動画の見どころ4/10枚目 J-ALEX Phase III Study Design
動画の見どころ5/10枚目 Global ALEX Study Design
動画の見どころ6/10枚目 PFS: analysis by subgroups
動画の見どころ7/10枚目 Second-Generation ALK TKIs are the New First- Line Standard of Care
動画の見どころ8/10枚目 Different ALK TKIs have Different Activity Against ALK Resistance Mutations
動画の見どころ9/10枚目 Lorlatinib is Effective Against ALK G1202R and Other Resistance Mutations
動画の見どころ10/10枚目 Next-Generation ROS1 Inhibitors
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YouTube-LUNGevityFoundation
2015/06/17動画の見どころ1/10枚目 What are targeted therapies?
動画の見どころ2/10枚目 How do targeted therapies work?
動画の見どころ3/10枚目 What are tyrosine kinase inhibitors (TKIs)?
動画の見どころ4/10枚目 How do ALK inhibitors work?
動画の見どころ5/10枚目 Side effects
動画の見どころ6/10枚目 What are the side effects of ALK inhibitors?
動画の見どころ7/10枚目 Low testosterone
動画の見どころ8/10枚目 Serious side effects
動画の見どころ9/10枚目 Acquired resistance to ALK inhibitors
動画の見どころ10/10枚目 Conclusion
... crizotinib as first-line therapies for advanced non-small cell lung cancer (NSCLC). In addition to alectinib, Dr Camidge discusses the ...
YouTube-VJOncology
2018/08/22This video shows you how to pronounce Crizotinib.
YouTube-Pronunciation Guide
2015/03/02A phase 1 clinical trial of the drug crizotinib achieved remissions, for 10 of the children participating in a clinical study carried out by the multicenter ...
Children's Hospital of Philadelphia-The Children's Hospital of Philadelphia
2017/03/11... Crizotinib in the First-line Treatment of Patients (pts) with Advanced ALK-Positive Non-Small Cell Lung Cancer (NSCLC): Results of the Phase 3 CROWN Study.
Daily Reporter-European Society for Medical Oncology (ESMO)
2020/09/19... crizotinib. Molecular profiling of circulating tumor DNA (ctDNA) and ... crizotinib. This interview took place at the American Society of ...
YouTube-VJOncology
2022/06/07These changes in the make the lymphoma cells grow out of control. An ALK-inhibiting drug called crizotinib was developed to target the gene directly, which ...
Children's Hospital of Philadelphia
2014/10/15... crizotinib-resistant tumors harbor ALK resistance mutations 29:26 Spectrum of resistance mechanisms – results from repeat biopsy program 31 ...
YouTube-Cell Signaling Technology, Inc.
2020/04/25動画の見どころ1/10枚目 Welcome
動画の見どころ2/10枚目 Combinatorial Drug Screen
動画の見どころ3/10枚目 Could you use this approach as a mechanism to sensitize tumor cells?
動画の見どころ4/10枚目 Translocations
動画の見どころ5/10枚目 Approaches to overcoming resistance
動画の見どころ6/10枚目 Acquisition of Resistance
動画の見どころ7/10枚目 Inhibition of Critical Signaling Pathways
動画の見どころ8/10枚目 Predicting Clinical Mutations
動画の見どころ9/10枚目 Able-1 inhibitors
動画の見どころ10/10枚目 Closing Remarks
Edie was one of 27 neuroblastoma patients enrolled on the phase 1 trial of an ALK-inhibitor called crizotinib.
Children's Hospital of Philadelphia-The Children's Hospital of Philadelphia
2018/06/15... Crizotinib and Dacomitinib in combination and had pretty significant side effects from that. It wasn't working for me, so after about six ...
YouTube-Dana-Farber Cancer Institute
2015/02/09... crizotinib for two years to test if additional targeted therapies improved survival in these patients beyond what we get with chemotherapy ...
Facebook-National Cancer Institute
2016/11/17Lung Cancer Non-Small Cell Lung Cancer Brigatinib Crizotinib · ALTA-1L. Raffaele Califano, MD, of The Christie NHS Foundation Trust, Manchester ...
VJOncology-VJOncology
2021/01/29