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What is HER2?
Brain metastases in HER2-positive Breast Cancer
New drugs in clinical trials for HER2-positive Breast Cancer
What are the side effects?
New HER2 inhibitors
New drug: unamilumab
What's new in research for brain metastases?
How many patients are in clinical trials?
What qualifies success in a trial?
How is HER2 tested?
What is HER2-positive Breast Cancer?
What is HER2?
How do you know if you are HER2 positive?
What is Herceptin?
Why consider chemotherapy before surgery?
What are the benefits of neoadjuvant chemotherapy?
What are the benefits of chemotherapy for HER2 positive breast cancer?
Breast Cancer School for Patients Recommendations
Clinical Trials
Conclusion
Opening Remarks
Development of Trastuzumab (Herceptin)
What are the benefits of combining trastuzumab and pertuzumab?
Development of antibody-drug conjugates
Waterfall plots
Important questions in HER2-positive MBC
Predicting who can safely stop therapy
Efficacy of trastuzumab in brain metastases
What is the difference between Herceptin and Kigentini?
Closing Remarks
Intro
Breast Cancer Diagnosis
What do we know about HER2-positive Breast Cancer now versus 20 years ago?
What is the difference between standard therapy and targeted therapy?
How do you determine in what order to administer therapies?
What was your treatment plan?
When do patients require targeted therapies?
Risks and benefits of treatment
New treatment for Breast Cancer
Conclusion
Intro
What is HER2+ve cancer?
What does the HER2 protein do?
What does it mean if a breast cancer is HER2 positive?
How does your doctor know if your cancer is HER2 positive?
How is HER2 positive cancer treated?
What are the anti-HER2 drugs?
Monoclonal Antibodies
Herceptin
Perjeta
Phesgo
Who gets Herceptin, Perjeta and Phesgo?
Antibody Drug Conjugates
Kadcyla
Enhertu
Kinase Inhibitors
Tykerb
Tukysa
Nerlynx
Why you might not get Herceptin
What are the side effects of anti-HER2 treatment
HER2 low cancers and Enhertu