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Introduction
What is Enterprise Content Management (ECM)?
The Six Pillars of ECM
Capturing Content in OnBase
Managing Content in OnBase
Access Content in OnBase
Integrate OnBase with Other Applications
Measuring & Reporting on Your Data in OnBase
Store Your Data Securely in OnBase
How to Get Started
Customer Examples
Why ECM?
Fibrosis and extracellular matrix remodeling is essential for many pathologies
ECM & collagens controls cell development and fate
Different collagens - different structures and functions
Proteins have many different domains - selection of the right epitope
We need to define the disease by the tissue turnover profile
Low PRO-C2 is associated with progression in OA
High levels of PRO-3 identify responders to anti- fibrotic activity of farglitazar
MMP degraded and cross-linked type Ill collagen
Conclusion - collagen fragments are a crystal ball