What is IVIG?

Who can be an IVIG donor?

When is IVIG used?

When might a myeloma patient's doctor suggest using IVIG?

In an individual has IgG myeloma, how are levels of norma IgG antibodies determined?

How does IVIG work?

How often will a myeloma patient need to get IVIG infusions?

How is IVIG administered?

Are any pre-medications given before the IVIG infusion?

Would taking aspiring help manage the risk of developing blood clots?

Can IVIG be given on the same day as other myeloma treatments?

Which myeloma therapies are most likely to potentially cause a need for IVIG?

When is IVIG treatment stopped, or is it ongoing?

Does IVIG treatment interfere with vaccinations?

Does IVIG have COVID antibodies in its formulation? Can it provide protection against COVID?

History of IVIG Therapy

Plasma Pool Requirements

Convenient Administration with Flexible Scheduling

Stabilizers: Sucrose

Sodium content in IVIG

Stabilizing Agents

Management of Adverse Reactions

Infusion Rate Guidelines

Considerations for IVIG Therapy

Conclusion

Disclaimer

Plasma Donation

What IVIG is NOT

Selective Antibody Deficiencies

Ig Brands

Pre-medication for IVIG

Closing Thoughts

Can you increase IgM?

IV vs SubQ

Closing Remarks

Megan Curran, MD, What Is IVIG

Immune System Overview

IVIG Overview

How Do We Think IVIG Works?

IVIG Studies

IVIG Side Effects

IV vs. Subcutaneous (SubQ)

Tips and Tricks for Those Receiving IVIG

Cure JM Co-Founder Tom Hume Asks Panel to Introduce Themselves (James Sheets, CVS Pharmacy, Maddie Davis, JDMer, Who Switched from IVIG to SubQ, Michelle Vogel, CSI Pharmacy, Colleen Marchetta)

Questions from the Audience

Can You Do IVIG If Your Child Has High Platelets?

Is There a Connection Between Plasma Collection and the IVIG Shortage?

SuqQ Overview

Maddie Davis Demonstrates SubQ, Narrated by a Nurse from CSI Pharmacy

How Does the Cost of SubQ Compare to the Cost of IVIG?

Is Thrombosis a Risk for SubQ?

Are There Insurance Issues Switching from SubQ to IVIG or Vice Versa?

Differences Between Receiving SubQ/IVIG In-Patient or At-Home?

Are There Many Reports of Adverse Reactions During Home Infusions?

If You Have Bad Side Effects to IVIG, Will You Have the Same Side Effects with SubQ?

Any Tips on How to Talk to You Doctor About Switching from IVIG to SubQ?

What Are the Differences In Dosage/Dosage Over Time Between IVIG and SubQ?

Are There Relevant, Ongoing Clinical Trials for SubQ?

Do the SubQ Injection Sites Leave Visible Marks?

Do We Know of Any Risks Associated with the Use of Long-Term Usage of IVIG?

Intro

What is IVIG?

Risks of IVIG

Allergic reactions

IVIG Side Effects

Conclusion

Intro

What is Gamma Globulin?

Common Variable Immunodeficiency (CVID)

Is there a cost difference?

Other things to think about

What happens when you get your first infusion?

IgG Levels

IV Ig vs SubQ Ig

Systemic Side Effects

Disclosures

Who does DM affect?

Dermatomyositis (DM) Typical Symptoms

ProDERM Study Endpoints Primary and Secondary Objectives

ProDERM Population Parameters

GAM10-08 (ProDERM) Study Design

Mean Total Improvement Score (TIS) from Week 4 to 40

Summary

Ivig

Issues

Infusion Pumps

Igg Therapy Is Not Approved in Jdms

Health Insurance

High Deductible Plans

Don'ts

Phase Three Double-Blinded Randomized Control Trial That Was Done in Adults Dermatomyositis

Is Ivig Good for a Patient Who Is Positive for Skin and Calcium Buildup of Dermatomyositis but Not the Muscle Weakness Antibody

How Do You Determine How Often a Child Should Receive Ivig

Sélection des donneurs de plasma

Troubles médicaux concomitants

Hydratation

Sodium

Teneur en immunoglobulines A

Sélection du produit

Médications antihistaminiques

Mesures de confort

Étude de cas 2

Conclusion

Ivig Stands for Intravenous Immune Globulin

Immune System

B Cells and T Cells

Patients Can Do To Prepare for Their Ivig Infusion

Side Effects

Pre-Medication

Symptoms

The Ivig Rate

Ivig Works

Aseptic Meningitis