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Initial Historical Accounts
2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides
Therapy Definitions
Diagnostic Testing Recommendations
GCA Case - Initial Treatment Considerations
GCA Case - New Visual Symptoms
Clinical/Laboratory Monitoring Recommendations
Disease Relapse While on Glucocorticoids Recommendations
Disease Relapse with Symptoms of Cranial Ischemia Recommendations
Highlights of GCA Recommendations
Goals of Therapy
Prevent Cranial Ischemic Complications
Glucocorticoids Cause Adverse Events
What about Methotrexate as a Steroid Sparing Agent
Are We Treating the Inflammatory Manifestations but Not Vasculopathy
Polymyalgia Rheumatica
Adjunctive Therapy
Methotrexate
Fda Approved Cyrillumab for Refractory Polymyalgia Rheumatica
Rapid Taper
Introducing Sebastian Unizony, MD.
What is Giant Cell Arteritis (GCA)?
How GCA commonly presents.
Current treatments.
Questions about GCA.
Q: After being on a treatment plan for two years with no flares is there a chance of losing vision as prednisone is reduced?
Q: What is the most common diagnostic test used for monitoring ongoing disease?
Q: Are there any genetic depositions for GCA?
Audience Survey: Experience with clinical studies.
Understanding clinical trials.
Studying treatment options for GCA.
Clinical Trials 101-- A Glossary.
Ethical and scientific principles and guidelines.
Vasculitis clinical trials.
Abatacept (orenica) for GCA.
Mavrilimumab for GCA.
Ongoing study of abatacept.
Ongoing study of upadacitinib (rinvoq).
Ongoing study of guselkumab (tremfya).
GUSTO Study (Switzerland) Can we use less than six months of steroids?
Ultimate goal of clinical trials in GCA in the near future.
Three online resources.
Are newly diagnosed patients allowed to participate in clinical studies?
Why should I participate in a clinical study if my current treatment protocol is working?
Thank you and wrap up.