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8th May 1980, smallpox was officially declared eradicated worldwide
Over 300 million people died from this virus in the 20th century.
In 1796 the world's first vaccine against any disease was developed.
In 1958, having contained the disease, the government of the USSR
At the height of the Cold War, the Soviet Union
In solidarity, countries worked to fight the virus.
a 10-year Intensified Smallpox Eradication Programme.
Why is this important today?
The vital lessons learned from smallpox are being used to fight polio, Ebola
As we did 40 years ago with smallpox, we can and we will beat COVID-19.
Smallpox Vaccination with ACAM2000: Introduction
ACAM2000 • Aventis Pasteur Smallpox Vaccine (APSV)
Replication-competent vaccines: ACAM2000 and APSV
MVA: attenuated strain of live vaccinia virus
Description and Preparation of the ACAM2000 Smallpox Vaccine, Administration Technique Using a Bifurcated needle, and Description of a "Vaccine Take"
How to Care for the Smallpox Vaccination Site and How to Prevent the Spread of Vaccinia Virus
Common Reactions and Potential Serious Adverse Events Following Smallpox Vaccination
Chapter 3: How to Care for the Smallpox Vaccination Site and Prevent the Spread of Vaccinia Virus
Instructions to the Vaccinee
Wash hands after: • Direct contact with the vaccination site • Contact with any materials that might be contaminated
Keep the entire vaccination site covered
Change the bandage every 3 days (or sooner)
Throw scab away once it falls off
Do not scratch that itch!
Do NOT use salves, ointments, or creams
Do your own laundry
Keep the vaccination site dry
Chapter 4, Part C: Treatment of Smallpox Vaccine Adverse Effects
Eczema vaccinatum • Progressive vaccinia
VIGIV available from CDC for treatment of vaccine complications with more serious clinical manifestations
Investigational antiviral medications may be available from CDC for treatment of serious complications due to smallpox vaccine