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Deciphering the Secrets of Brain Development by Naofumi Uesaka, Department of Cognitive Neurobiology, Graduate School of Medical and Dental ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2024/03/12Toward understanding diversity of various disorder-specific myeloid cells by Takashi Satoh, Department of Immunology, Graduate School of ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2023/03/28Minimally Invasive Drug and Cell Delivery Systems Targeting the Posterior Segment of the Eye by Hirokazu Kaji, Department of Biomechanics, ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2023/03/02Clinical application of the digital dentures by Manabu Kanazawa Department of Digital Dentistry, Graduate School of Medical and Dental ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2023/02/28Infusion of 3D cellular structures might repair damaged intestine by Shiro Yui & Satoshi Watanabe Shiro Yui, Center for Stem Cell and ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2022/02/09Dental OCT - A Novel Imaging Technique without the use of X rays by Yasushi Shimada Department of Cariology and Operative Dentistry, ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2023/02/28... TMDU Research Activities https ... (TMDU) E-mail:joji.kusuyama.bsin(at)tmd.ac.jp ＊Please change (at) in e-mail ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2024/03/11TMDU Research Activities 2023-2024 by Takashi Ono and Yuji Ishida The “Wishbone” Charm that Restores the Hope for Bone Regeneration by ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2024/03/08The world's first Mini Organ transplantation to a patient with “Ulcerative Colitis (UC)” by Ryuichi Okamoto, Tomohiro Mizutani and Hiromichi ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2023/03/14Toward understanding mechanisms of chronic inflammation by Yumiko Oishi Department of Medical Biochemistry, Graduate School of Medical and ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2024/02/26TMDU Center for Infectious Disease Education and Analysis (TCIDEA) by Yoshiaki Gu, Tomoko Yazawa and Hiroaki Takeuchi Yoshiaki Gu, ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
3週間前Link between chronic kidney disease and cardiovascular disease explained by Shintaro Mandai, Department of Nephrology, Graduate School of ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2024/03/13... (TMDU) Precision Engineering Design for Biofunctional Repair and ... TMDU Research Activities https://www.tmd.ac.jp/english/research_activities/
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2023/02/28Tokyo Medical and Dental University (TMDU) Movie. 16K views · 6 years ago ...more. Tokyo Medical and Dental University東京医科歯科大学.
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2018/03/08動画の見どころ1/10枚目 History
動画の見どころ2/10枚目 Our Vision
動画の見どころ3/10枚目 History of TMDU
動画の見どころ4/10枚目 The School of Dentistry
動画の見どころ5/10枚目 Medical Treatment at TMDU
動画の見どころ6/10枚目 Heliport
動画の見どころ7/10枚目 Dental Hospital
動画の見どころ8/10枚目 Internationalization of the Curriculum
動画の見どころ9/10枚目 Research Centers Abroad
動画の見どころ10/10枚目 Our Mission
Introduction Video about TMDU produced by the Institute of Global Affairs. 2.2K views · 1 year ago ...more ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2022/12/19... (TMDU) Protein Secrets Unveiled: New molecular insight of protein ... TMDU Research Activities https://www.tmd.ac.jp/english ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2024/03/06... (TMDU) Informatics and Artificial Intelligence for Biomedicine ... TMDU Research Activities https://www.tmd.ac.jp/english/research_activities ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
1か月前... (TMDU) Pre-basophils: a basophil origin story https://www.tmd.ac.jp/english/press-release/20220706-1/ TMDU Research Activities https://www ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2024/01/31... (TMDU) Tears in Tokyo: Muscle–tendon injuries during Olympic competition can spell heartbreak https://www.tmd.ac.jp/english/press-release ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2023/03/08A new agent for the brain diseases: mRNA by Keiji Itaka & Yuta Fukushima, Department of Biofunction Research, Institute of Biomaterials and ...
YouTube-Tokyo Medical and Dental University東京医科歯科大学
2022/01/30Synthetic mRNA encoding therapeutic proteins is incorporated into nano-scale carrier, and administered to target cells.
In the cells, the mRNA is released into the cytoplasm, followed by protein translation using the similar machinery for the regular processes of gene expression.
This system is based on block copolymer composed of hydrophilic segment of polyethylene glycol, and hydrophobic segment of polyamino acids.
We designed the polymer structure to provide specific biofunctions such as cell targeting, drug loading and release.
We applied the mRNA-loaded nanomicelle for the treatment of cerebral ischemic diseases, which would cause various neurologic disorders.
We used a rat model of transient global ischemia, called TGI, in which neuronal death is induced specifically in the vulnerable hippocampus, with gradually progressive manner for several days.
These are the histology sections of the hippocampus after the administration of BDNF mRNA.
Very interestingly, the mRNA administration on Day 2 provided the maximal effect of neuroprotection, even compared with the administration just after the TGI.
The therapeutic effect was confirmed by a behavioral test to analyze the memory function.
Finally, we investigated the target cells of mRNA, mRNA was mostly introduced into astrocytes.