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The purpose of the immune system is to protect the host from infectious pathogens
Innate immunity represents a first line of defense between host and microbe
Epithelial barriers physically exclude pathogens through a variety of mechanisms
Infection occurs once pathogens breach mechanical barriers and enter underlying tissue
Types of innate immune cells that respond to early stages of Infection
Phagocytes are a first line of defense following barrier disruption and microbial Invasion
Mechanisms of pathogen killing that are coupled to phagocytosis
Inflammation enables the recruitment of additional leukocytes to control infection
Lecture 2a: Summary and Key Points