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The chemical make-up can be more potent than many illegal drugs.
Like illegal drugs, they are classified as either stimulants, sedatives or psychedelics.
Legal highs can be bought online, in convenience stores and head shops retail outlets specializing in smoking paraphernalia.
A reported 670,000 15 to 24-year-olds in the U.K. admitted to using a legal high at least once.
In an attempt to tackle the problem, the British government has introduced the Psychoactive Substances Act.